pentobarbital will reduce the level or effect of saxagliptin by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Minimal/Importance Mysterious.
pentobarbital will reduce the extent or effect of loratadine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Watch.
pentobarbital will minimize the level or influence of bexarotene by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Watch.
Contraindicated (1)pentobarbital decreases levels of panobinostat by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Potent CYP3A4 inducers can lessen panobinostat levels by ~70% and lead to treatment method failure.
pentobarbital will lessen the level or effect of pimozide by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Small/Importance Unfamiliar.
Keep track of Closely (2)pentobarbital will lower the level or influence of oliceridine by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Watch. If coadministration with a CYP3A4 inducer is essential, consider rising oliceridine dose until finally steady drug results are accomplished; watch for indications of opioid withdrawal.
pentobarbital will minimize the level or effect of stiripentol by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Prevent or Use Alternate Drug. If struggling to avoid coadministration of stiripentol with strong CYP3A4 inducers, increase stiripentol dose.
pentobarbital will lessen the level or outcome of elbasvir/grazoprevir by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. The therapeutic influence of elbasvir/grazoprevir can be reduced if coadministered with strong CYP3A inducers which is therefore contraindicated.
pentobarbital will decrease the level or impact of tamoxifen by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Monitor.
pentobarbital will reduce the extent or outcome of buspirone by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Check.
Insomnia would be the perception or complaint of insufficient or bad-quality sleep thanks to trouble slipping asleep; waking up frequently in the course of the night with problems returning to rest; waking up way too early in the morning; or unrefreshing slumber.
pentobarbital will minimize the extent or effect of irinotecan by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Watch.
pentobarbital increases toxicity of methoxyflurane by increasing metabolism. Contraindicated. Amplified metabolism of methoxyflurane to nephrotoxic compounds.
pentobarbital will lessen the level or impact of roflumilast by influencing hepatic/intestinal enzyme CYP3A4 metabolism. more info Contraindicated. Coadministration not suggested; solid cytochrome P450 enzyme inducers reduce systemic publicity to roflumilast and will lessen the therapeutic efficiency